Cent Eur J Public Health 2023, 31(Suppl 1)
Biological aspects of selected diseases in European population
Preface
Janka Poráčová
Cent Eur J Public Health 2023, 31(Suppl 1):3 
This Supplementum of the Central European Journal of Public Health brings new scientific knowledge and results regarding studies focused on the prevalence of some diseases in medicinal staff in a selected location in eastern Slovakia in connection with the COVID-19 pandemic, as well as the health status and hygienic behaviour of pregnant women in Hungary during this period. Other scientific works report the results of the study of the serious civilizational disease diabetes mellitus type 2 from the point of view of the association of biochemical markers and the genotype of the VDR gene, the influence on the occurrence and course of diabetic retinopathy...
Diabetes mellitus and its influence on the incidence and process of diabetic retinopathy
Janka Poráčová, Melinda Nagy, Marta Mydlárová Blaščáková, Mária Konečná, Vincent Sedlák, Mária Zahatňanská, Tatiana Kimáková, Hedviga Vašková, Viktória Rybárová, Mária Majherová, Ivan Uher
Cent Eur J Public Health 2023, 31(Suppl 1):S4-S9 | DOI: 10.21101/cejph.a7838
Objectives: The main aim of the study was to show the effect of diabetes in relation to the gender of the patients, duration of the disease, and on the incidence of diabetic retinopathy. In this study, we investigated the prevalence of these two diseases, pathological ocular changes and progression of disease occurrence in relation to the duration of the disease with respect to their impact on the quality of vision of the patient. Methods: The prospective observational cross-sectional study included 3,951 patients (1,838 males, 2,113 females) with diabetes mellitus from 7 districts of eastern Slovakia. Patients with diabetes mellitus and diabetic retinopathy...
Prevalence of COVID-19 antibodies in employees of St. Jacob Hospital in Bardejov
Mária Konečná, Mariana Maxinová, Eva Mihalcová, Anna Kutná, Vincent Sedlák, Marta Mydlárová Blaščáková, Mária Majherová, Meryem Yildiz, Jozef Fejér, Daniela Gruľová, Janka Poráčová
Cent Eur J Public Health 2023, 31(Suppl 1):S10-S14 | DOI: 10.21101/cejph.a7836
Objective: The COVID-19 disease caused by the SARS-CoV-2 virus belongs to the group of highly infectious diseases with increased mortality and morbidity in the population. Finding the presence of antibodies plays an important role while finding the number of individuals who overcame the disease or were vaccinated. Methods: A total of 250 employees of St. Jacob Hospital with Polyclinic, Bardejov, participated in our study, the blood samples were drawn from the index finger and processed with the help of the rapid Ag test for the detection of antibodies and venous blood using the ELISA method. The health workers (doctors, nurses, medical laboratory technicians,...
Monitoring of selected anthropometric and biochemical parameters in men and women in Bardejov District
Janka Poráčová, Mária Konečná, Vincent Sedlák, Marta Mydlárová Blaščáková, Meryem Yildiz, Viktória Rybárová, Mária Zahatňanská, Tatiana Kimáková, Melinda Nagy, Mária Majherová, Ivan Uher
Cent Eur J Public Health 2023, 31(Suppl 1):S15-S20 | DOI: 10.21101/cejph.a7839
Objectives: Metabolic and cardiovascular diseases represent a significant and ever-increasing problem, accounting for nearly one-third of all deaths and leading to significant morbidity. Lifestyle changes, which introduce new risk factors for cardiovascular disease, are leading to an increase in the risk of cardiovascular disease worldwide. The burden of cardiovascular disease can be reduced by careful risk reduction, and as such, primary prevention is an important priority for all. There is strong consensus among international guidelines regarding the necessity of smoking cessation, weight optimization, and the importance of exercise, while guidelines...
Prevention aid in qualitative analysis of dermatoglyphic patterns in relation to type 2 diabetes mellitus: a pilot study
Vincent Sedlák, Zuzana Pavelová, Mária Zahatňanská, Marta Mydlárová Blaščáková, Mária Konečná, Jana Gaľová, Zuzana Gogaľová, Jozef Fejér, Daniela Gruľová, Renáta Bernátová, Janka Poráčová
Cent Eur J Public Health 2023, 31(Suppl 1):S21-S25 | DOI: 10.21101/cejph.a7840
Objectives: The significant differences in the fingerprint pattern frequencies in type 2 diabetes mellitus (T2DM) patients and controls could be a possible way to identify patients with a risk of developing T2DM. The results could be used in the earlier diagnosis and treatment. The study was undertaken to find out the reliability of fingerprint patterns as a possible predictive tool for T2DM diagnosis. Methods: A total of 1,260 fingerprints were acquired using the optical contact sensor DactyScan 26i. The results of the qualitative analysis of the fingerprint pattern frequencies have been compared between T2DM patients and controls and also between...
Assessment of foot arch shape and health status of adult population from Eastern Slovakia
Jana Gaľová, Natália Kuková, Melinda Nagy, Mária Konečná, Andrea Babejová, Vincent Sedlák, Marta Mydlárová Blaščáková, Mária Zahatňanská, Tatiana Kimáková, Zuzana Pilát, Janka Poráčová
Cent Eur J Public Health 2023, 31(Suppl 1):S26-S30 | DOI: 10.21101/cejph.a7841
Background: The purpose of this study was to determine the foot arch shape and the associated health status in a selected sample of individuals belonging to the adult majority population of eastern Slovakia and to evaluate which of the observed factors are involved in the occurrence and development of foot arch abnormalities. Methods: The weight and height of probands were measured according to standard anthropometric methods using a personal scale and an anthropometer. The BMI index was calculated for each proband from the measured data. A Pod4Foot Classic podoscope was used to obtain the plantograms. The Chippaux-Smirak index method was used to evaluate...
Health literacy and patient rights awareness in ethnic Hungarian mothers in Eastern Europe
Renáta Erdei Jávorné, Melinda Nagy, Eszter Molnár, Réka Zsuzsánna Máthé, Emese Emőke Tóth-Batizán, Mária Konečná, Mária Zahatňanská, Marta Mydlárová Blaščáková, Janka Poráčová, Vincent Sedlák, Ágnes Sántha
Cent Eur J Public Health 2023, 31(Suppl 1):S31-S39 | DOI: 10.21101/cejph.a7894
Objectives: The paper proposes to identify the determinants of patients' rights awareness in mothers and to examine the relationship of health literacy with awareness of those rights. Methods: Our results are based on data from a convenience sample of 894 non-health professional ethnic Hungarian mothers from Hungary, Romania and Slovakia. Health literacy is measured with the HLS-EU-16 questionnaire. Results: Analysis of variance reveals a significant association of health literacy with patient rights awareness. Our results show that health literacy is the highest among patients who filed a complaint through formal channels and/or took legal measures...
Self-rated health status and hygienic behaviour of pregnant women in Hungary during the pandemic
Anita Katalin Grestyák Molnárné, Melinda Nagy, Ágota Barabás, Attila Csaba Nagy, Péter Takács, Ágnes Sántha, Mária Konečná, Vincent Sedlák, Andrea Babejová, Marta Mydlárová Blaščáková, Janka Poráčová, Renáta Erdei Jávorné
Cent Eur J Public Health 2023, 31(Suppl 1):S40-S47 | DOI: 10.21101/cejph.a7897
Objectives: The aim of our research was to investigate the self-rated health status, health behaviour and hygiene habits of pregnant women, and to explore the influencing factors during the pandemic. Methods: The sample included 1,200 pregnant women who gave birth in the most progressive institutions of the three examined counties in Hungary; 839 questionnaires were returned, based on which the willingness to answer can be said to be 69.9%. After data cleaning, 640 questionnaires were added to the database. Descriptive statistical analyses and correlation tests were performed, during which we used the Pearson's chi-square test and Fisher's exact test....
Examining the sleeping habits of preschool and elementary school children in Southern Slovakia
Eva Tóthová Tarová, Sarolta Darvay, Zoltán Fehér, Melinda Nagy, Iveta Szencziová, Dániel Dancsa, Veronika Himpán, Éva Winkler, Pavol Balázs, Mária Konečná, Vincent Sedlák, Mária Zahatňanská, Renáta Bernátová, Janka Poráčová
Cent Eur J Public Health 2023, 31(Suppl 1):S48-S54 | DOI: 10.21101/cejph.a7896
Objectives: Our research aimed to examine children's sleeping habits from preschool to the end of elementary school age. Developing proper sleeping habits in childhood is essential, as it is decisive for the rest of our lives. Methods: A total of 339 children (160 males and 179 females) took part in the research, of which 145 were preschool-age children (3-7 years old), 72 lower-grade elementary school children (6-11 years old), and 122 upper-grade elementary school children (12-16 years old). The questionnaire was completed in a paper form (elementary school students) and online (kindergarten children). Results: The research results show that most...
Nutrition habits and physical activity of disabled adolescents in Hungary
Ágota Barabás, Melinda Nagy, Anita Katalin Grestyák Molnárné, Attila Csaba Nagy, Viktoria Pazmany, Mária Zahatňanská, Mária Konečná, Vincent Sedlák, Marta Mydlárová Blaščáková, Janka Poráčová, Renáta Erdei Jávorné
Cent Eur J Public Health 2023, 31(Suppl 1):S55-S61 | DOI: 10.21101/cejph.a8058
Objectives: The overall aim of the research is to gain insight into the lifestyle and health behaviour of young people with disabilities aged 12-18 years, and to learn about the factors shaping their health. In this study, our aim was to investigate the eating habits and physical activity of adolescents with disabilities and the influencing factors. Methods: The study's source population was young people aged 12-18 with disabilities in the Szabolcs-Szatmár-Bereg County. A total of 239 completed questionnaires were processed and analysed. Boys were overrepresented in the study. Results: The results show that inadequate eating habits also exist in the...
Use of bioimpedance in prevention of sarcopenia in the elderly
Mária Konečná, Janka Poráčová, Vincent Sedlák, Jana Gaľová, Andrea Babejová, Mária Zahatňanská, Tatiana Kimáková, Melinda Nagy, Renáta Bernátová, Milan Bernát, Marta Mydlárová Blaščáková
Cent Eur J Public Health 2023, 31(Suppl 1):S62-S68 | DOI: 10.21101/cejph.a7895
Objectives: Physiological ageing is associated with major and progressive changes in body composition, particularly in the decline of fat-free mass, which puts older individuals at risk of geriatric syndromes such as sarcopenia and sarcopenic obesity. Bioimpedance analysis noninvasively allows the determination of body composition, thus being able to rapidly assess primary risk factors leading to sarcopenia prediction. Methods: We conducted a study of 180 probands, 120 females (66.7%) with a mean age of 76.23 (SD = 9.29) years and 60 males (33.3%) with a mean age of 74.01 (SD = 8.99) years in cooperation with facilities for the elderly and with the...
Level of biochemical parameters in patients with type 2 diabetes mellitus depending on the genotype of the FokI polymorphism in the vitamin D3 receptor (VDR gene)
Mária Konečná, Janka Poráčová, Melinda Nagy, Mária Majherová, Jana Gaľová, Zuzana Gogaľová, Hedviga Vašková, Marta Mydlárová Blaščáková, Daniela Gruľová, Vincent Sedlák
Cent Eur J Public Health 2023, 31(Suppl 1):S69-S74 | DOI: 10.21101/cejph.a7837
Objectives: Diabetes mellitus type 2 (T2DM) is a multifactorial and polygenic disorder characterised by chronic hyperglycaemia accompanied by impaired lipid, carbohydrate, and protein metabolism. The disease is associated with several genetic polymorphisms, including the FokI polymorphism in the vitamin D receptor (VDR) gene. Methods: We conducted a study of 327 probands (191 T2DM patients, 136 controls), with a mean age 65.06 (SD ± 10.88) years of patients with T2DM and 58.89 (SD ± 6.59) years in the healthy probands. We investigated the association between FokI polymorphism and biochemical parameters in T2DM patients in the Slovak population....
Association of the PDE4D gene variant with selected markers in individuals with ischaemic heart disease: a pilot study
Marta Mydlárová Blaščáková, Katarína Hricová, Katarína Mašlejová, Mária Majherová, Hedviga Vašková, Janka Poráčová, Renáta Bernátová, Mária Konečná, Vincent Sedlák
Cent Eur J Public Health 2023, 31(Suppl 1):S75-S81 | DOI: 10.21101/cejph.a7843
Objective: The aim of the study was to evaluate the variant (rs2910829) of the PDE4D gene in relation to its influence on biochemical, anthropometric and physiological parameters in patients with coronary artery disease and healthy subjects of the Eastern Slovak population. Methods: The male group consisted of 72 individuals and the female group consisted of 132 individuals. On the basis of clinical screening the subjects were divided into two groups - with ischaemic heart disease and control group. Genomic DNA was isolated from peripheral blood using a commercial NucleoSpin® Blood Machenery-Nagel kit. Molecular genetic analysis...
Polymorphisms rs562556 and rs2479409 of the PCSK9 gene associated with obesity and cardiovascular disease
Hedviga Vašková, Janka Poráčová, Miriama Šlebodová, Soňa Kalafutová, Mária Konečná, Vincent Sedlák, Tatiana Kimáková, Marta Mydlárová Blaščáková
Cent Eur J Public Health 2023, 31(Suppl 1):S82-S88 | DOI: 10.21101/cejph.a7844
Objective: The primary objective was to comprehensively assess the association between single nucleotide polymorphisms (rs562556 and rs2479409) in the PCSK9 gene with biochemical parameters - C-reactive protein (CRP), glucose (GLU), triglyceride (TAG), low-density lipoprotein cholesterol (LDL CHOL), non-high-density lipoprotein cholesterol (non HDL CHOL), high-density lipoprotein cholesterol (HDL CHOL), cholesterol (CHOL), and anthropometric parameters (visceral fat), overweight/obesity and cardiovascular risk. Methods: A total of 71 women aged 23-64 years were divided into three groups based on body mass index (BMI). BMI ≥ 25/≥...
Initial screening of the rs104893657 variant of the PAX8 gene in women with hypothyroidism from Northeastern Slovakia
Marta Mydlárová Blaščáková, Barbora Homjáková, Melinda Nagy, Janka Poráčová, Zuzana Lörinczová, Pavol Makovický, Tatiana Kimáková, Vincent Sedlák, Mária Konečná
Cent Eur J Public Health 2023, 31(Suppl 1):S89-S94 | DOI: 10.21101/cejph.a7842
Objective: Thyroid diseases are among the most common endocrinopathies and metabolic disorders. Hypothyroidism is caused by insufficient production of thyroid hormones with a higher prevalence in women. Causes for the development of endocrine diseases may be mutations in genes that encode peptide hormones. The aim of this scientific study was to determine the genotype and allele frequencies of the rs104893657 variant of the PAX8 gene and to determine the genotype versus phenotype association. Methods: The study population consisted of 135 women from northeastern Slovakia who were divided on the basis of screening into two groups: a control group...
Cytogenetic analysis of coke oven workers in Eastern Slovakia
Vincent Sedlák, Anton Bujňák, Andrej Gajdoš, Dagmar Gajdošová, Janka Poráčová, Mária Konečná, Jozef Fejér, Daniela Gruľová, Hedviga Vašková, Marta Mydlárová Blaščáková
Cent Eur J Public Health 2023, 31(Suppl 1):S95-S100 | DOI: 10.21101/cejph.a7845
Objective: Our study aimed to evaluate the extent of polycyclic aromatic hydrocarbon (PAH) exposure in coke oven workers from Eastern Slovakia by cytogenetic analysis of human peripheral lymphocytes. Methods: A total of 81 peripheral blood samples were collected from PAH-exposed workers (mean age 45.84 ± 9.73 years) and 30 samples constituted the control group (41.93 ± 15.39 years). The samples were processed using routine cytological analysis. Conventional cytogenetic analysis of human peripheral lymphocytes has been used to evaluate the effects of PAHs. Results: Comparison of the aberrant cells in the total exposed with the controls showed...